2024 研究成果

2024 研究成果

2024年

SARM1 regulates NAD+-linked metabolism and select immune genes in macrophages
Katharine A Shanahan, Gavin M Davis, Ciara G Doran, Ryoichi Sugisawa, Gavin P Davey, Andrew G Bowie
J Biological Chemistry 3 Jan 2024. doi: 10.1016/j.jbc.2023.105620

https://www.sciencedirect.com/science/article/pii/S0021925823026492

Deoxycytidine Kinase Inactivation Enhances Gemcitabine Resistance and Sensitizes Mitochondrial Metabolism Interference in Pancreatic Cancer
Dash S, Ueda T, Komuro A, Honda M, Sugisawa R, Okada H.
Cell Death & Disease (2024) 15:131; https://doi.org/10.1038/s41419-024-06531-x

https://www.nature.com/articles/s41419-024-06531-x

ACA-28, an ERK MAPK Signaling Modulator, Exerts Anticancer Activity through ROS Induction in Melanoma and Pancreatic Cancer Cells
Takasaki T, Hamabe Y, Touchi K, Khandakar GI, Ueda T, Okada H, Sakai K, Nishio K, Tanabe G, Sugiura R
Oxidative Medicine and Cellular Longevity Volume 2024 | Article ID 7683793 | https://doi.org/10.1155/2024/7683793

https://www.hindawi.com/journals/omcl/2024/7683793/

SARM1 regulates pro-inflammatory cytokine expression in human monocytes by NADase-dependent and -independent mechanisms
Sugisawa R, Shanahan KA, Davis GM, Davey GP, Bowie AG
iScience (2024) 27 (6) 109940; DOI:10.1016/j.isci.2024.109940

https://www.cell.com/iscience/fulltext/S2589-0042(24)01162-3

Vgll2 as an integrative regulator of mitochondrial function and contractility specific to skeletal muscle
Honda M, Inoue R, Nishiyama K, Ueda T, Komuro A, Amano H, Sugisawa R, Dash S, Shirakawa J, Okada H
J Cell Physiol. 2024 Sep 17:e31436 109940; DOI:10.1002/jcp.31436

https://onlinelibrary.wiley.com/doi/10.1002/jcp.31436